Beware Causes of Breast Cancer
Breast cancer cases continues to rise. According to data from GLOBOCAN (IARC), approximately 1.67 million new cases of breast cancer were diagnosed in 2012 (25% of all cancers). Meanwhile, based on national data obtained from the Ministry of Health, breast cancer ranks second leading cause of cancer in women. Given the high figures, awareness about breast cancer is very important.
Breast cancer. It is reasonable to find out what pennyebabnya when you hear the name of this one disease. Various factors can increase the risk of breast cancer. Unfortunately, there has not been known exactly what causes it. The only thing that is known is that breast cancer is associated with damage to cells' DNA.
DNA is the chemical compound in the cells that regulate genes. DNA is not just related to your facial resemblance with parents or siblings; some genes also control the growth, division and cell death. Normal breast cells become cancerous due to changes (mutations) in the DNA. Some DNA mutations are hereditary. However, most changes in the DNA of breast cancer are more prevalent due to lifestyle than genetic.
Then, why breast cancer can happen to someone? Cancer occurs when cells in the tissues grow and develop abnormally and attack healthy cells. Stacking these cells can form a mass of tissue called a lump or tumor. Breast cancer occurs when a malignant tumor develops in the breast. Such cells can spread and get into the blood or lymph vessels connected to tissues throughout the body.
Changes and damage in the BRCA1 and BRCA2 genes (which are restraining the growth of abnormal cells) may increase the risk of breast cancer. Changes in these genes can be inherited from parents. When one of these genes changed, the gene can not withstand abnormal cell growth making it easier for cancer cells to grow.
Women who have a mother, sister, or child with a history of breast cancer are also more vulnerable to two to three times the experience of breast cancer. In addition, radiation and carcinogenic chemicals also contribute to changes in the DNA of cells to become cancer cells.
Breast cancer is also associated with exposure to the hormone estrogen. The hormone estrogen effect as it can 'tell' cells to divide. That is, the more cells divide, the more likely the cells become abnormal and become cancer cells.
Yes, there are many factors that can trigger breast cancer. Women who have a family history of breast cancer is at greater risk of developing breast cancer. However, risk factors do not directly make sure you get breast cancer. Beware and do examinations early.